CCR5Δ32, CCR2-64I, and SDF1-3′ a polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population

Cesar Paz-Y-Mino; Santiago A. Morillo; Ana P. Celi; Tania Witte; María José Muñoz Guijarro; Juan Carlos Collantes; Paola E. Leone

CCR5Δ32, CCR2-64I, and SDF1-3′ a polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population

Cesar Paz-Y-Mino^*
, Santiago A. Morillo
, Ana P. Celi
, Tania Witte
, María José Muñoz Guijarro
, Juan Carlos Collantes
, Paola E. Leone

^*Corresponding author for this work

Pontificia Universidad Católica del Ecuador
Universidad de las Fuerzas Armadas ESPE

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The aim of this study was to determine the allele frequencies of genetic variants CCR5Δ32, CCR2-64I, and SDF1-3′A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.

Original language	English
Pages (from-to)	521-526
Number of pages	6
Journal	Human Biology
Volume	77
Issue number	4
State	Published - Aug 2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

CCR2-64I
CCR5Δ32
Chemokines
Disease prognosis
Ecuadorian population
HIV-1 infection
SDF1-3′A

Cite this

@article{25c1b98c22cd479bac644f19eb36b19f,

title = "CCR5Δ32, CCR2-64I, and SDF1-3′ a polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population",

abstract = "The aim of this study was to determine the allele frequencies of genetic variants CCR5Δ32, CCR2-64I, and SDF1-3′A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.",

keywords = "CCR2-64I, CCR5Δ32, Chemokines, Disease prognosis, Ecuadorian population, HIV-1 infection, SDF1-3′A",

author = "Cesar Paz-Y-Mino and Morillo, \{Santiago A.\} and Celi, \{Ana P.\} and Tania Witte and Guijarro, \{Mar{\'i}a Jos{\'e} Mu{\~n}oz\} and Collantes, \{Juan Carlos\} and Leone, \{Paola E.\}",

year = "2005",

month = aug,

language = "Ingl{\'e}s",

volume = "77",

pages = "521--526",

journal = "Human Biology",

issn = "0018-7143",

publisher = "Wayne State University Press",

number = "4",

}

TY - JOUR

T1 - CCR5Δ32, CCR2-64I, and SDF1-3′ a polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population

AU - Paz-Y-Mino, Cesar

AU - Morillo, Santiago A.

AU - Celi, Ana P.

AU - Witte, Tania

AU - Guijarro, María José Muñoz

AU - Collantes, Juan Carlos

AU - Leone, Paola E.

PY - 2005/8

Y1 - 2005/8

N2 - The aim of this study was to determine the allele frequencies of genetic variants CCR5Δ32, CCR2-64I, and SDF1-3′A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.

AB - The aim of this study was to determine the allele frequencies of genetic variants CCR5Δ32, CCR2-64I, and SDF1-3′A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.

KW - CCR2-64I

KW - CCR5Δ32

KW - Chemokines

KW - Disease prognosis

KW - Ecuadorian population

KW - HIV-1 infection

KW - SDF1-3′A

UR - https://www.scopus.com/pages/publications/28844440084

M3 - Artículo

C2 - 16485782

AN - SCOPUS:28844440084

SN - 0018-7143

VL - 77

SP - 521

EP - 526

JO - Human Biology

JF - Human Biology

IS - 4

ER -

CCR5Δ32, CCR2-64I, and SDF1-3′ a polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population

Abstract

UN SDGs

Keywords

Other files and links

Fingerprint

Cite this