Induced hyperprolactinaemia does not alter FSH binding or ABP secretion in the rat testis

Jaime Guevara‐Aguirre; Guillermo Schoener; Alfredo Ulloa‐Aguirre; Gregorio Pérez‐Palacios; Fernando Larrea

doi:10.1111/j.1365-2605.1986.tb00900.x

Induced hyperprolactinaemia does not alter FSH binding or ABP secretion in the rat testis

Jaime Guevara‐Aguirre
, Guillermo Schoener
, Alfredo Ulloa‐Aguirre
, Gregorio Pérez‐Palacios
, Fernando Larrea^*

^*Corresponding author for this work

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The effects of induced hyperprolactinaemia in male Wistar rats were studied by grafting two pituitary glands under the kidney capsule. Transplants were performed at 15 and 60 days of age, and rats killed 4 weeks later when tissue and serum samples were obtained. Serum concentrations of LH were reduced significantly in rats grafted at 60 days of age, whereas no change was observed in rats grafted at 15 days of age. Serum testosterone levels were slightly suppressed only in the older group of grafted rats. Testicular FSH receptors and the epididymal content of androgen‐binding protein (ABP) were not modified by induction of hyperprolactinaemia. The results indicate that hyperprolactinaemia was not associated with changes in at least two functional parameters of the tubular compartment of the rat testis.

Original language	English
Pages (from-to)	381-392
Number of pages	12
Journal	International Journal of Andrology
Volume	9
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2605.1986.tb00900.x
State	Published - Oct 1986
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

FSH‐receptor
LH
prolactin
testis

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10.1111/j.1365-2605.1986.tb00900.x

Cite this

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title = "Induced hyperprolactinaemia does not alter FSH binding or ABP secretion in the rat testis",

abstract = "The effects of induced hyperprolactinaemia in male Wistar rats were studied by grafting two pituitary glands under the kidney capsule. Transplants were performed at 15 and 60 days of age, and rats killed 4 weeks later when tissue and serum samples were obtained. Serum concentrations of LH were reduced significantly in rats grafted at 60 days of age, whereas no change was observed in rats grafted at 15 days of age. Serum testosterone levels were slightly suppressed only in the older group of grafted rats. Testicular FSH receptors and the epididymal content of androgen‐binding protein (ABP) were not modified by induction of hyperprolactinaemia. The results indicate that hyperprolactinaemia was not associated with changes in at least two functional parameters of the tubular compartment of the rat testis.",

keywords = "FSH‐receptor, LH, prolactin, testis",

author = "Jaime Guevara‐Aguirre and Guillermo Schoener and Alfredo Ulloa‐Aguirre and Gregorio P{\'e}rez‐Palacios and Fernando Larrea",

year = "1986",

month = oct,

doi = "10.1111/j.1365-2605.1986.tb00900.x",

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volume = "9",

pages = "381--392",

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number = "5",

}

TY - JOUR

T1 - Induced hyperprolactinaemia does not alter FSH binding or ABP secretion in the rat testis

AU - Guevara‐Aguirre, Jaime

AU - Schoener, Guillermo

AU - Ulloa‐Aguirre, Alfredo

AU - Pérez‐Palacios, Gregorio

AU - Larrea, Fernando

PY - 1986/10

Y1 - 1986/10

N2 - The effects of induced hyperprolactinaemia in male Wistar rats were studied by grafting two pituitary glands under the kidney capsule. Transplants were performed at 15 and 60 days of age, and rats killed 4 weeks later when tissue and serum samples were obtained. Serum concentrations of LH were reduced significantly in rats grafted at 60 days of age, whereas no change was observed in rats grafted at 15 days of age. Serum testosterone levels were slightly suppressed only in the older group of grafted rats. Testicular FSH receptors and the epididymal content of androgen‐binding protein (ABP) were not modified by induction of hyperprolactinaemia. The results indicate that hyperprolactinaemia was not associated with changes in at least two functional parameters of the tubular compartment of the rat testis.

AB - The effects of induced hyperprolactinaemia in male Wistar rats were studied by grafting two pituitary glands under the kidney capsule. Transplants were performed at 15 and 60 days of age, and rats killed 4 weeks later when tissue and serum samples were obtained. Serum concentrations of LH were reduced significantly in rats grafted at 60 days of age, whereas no change was observed in rats grafted at 15 days of age. Serum testosterone levels were slightly suppressed only in the older group of grafted rats. Testicular FSH receptors and the epididymal content of androgen‐binding protein (ABP) were not modified by induction of hyperprolactinaemia. The results indicate that hyperprolactinaemia was not associated with changes in at least two functional parameters of the tubular compartment of the rat testis.

KW - FSH‐receptor

KW - LH

KW - prolactin

KW - testis

UR - https://www.scopus.com/pages/publications/0022915925

U2 - 10.1111/j.1365-2605.1986.tb00900.x

DO - 10.1111/j.1365-2605.1986.tb00900.x

M3 - Artículo

C2 - 3106245

AN - SCOPUS:0022915925

SN - 0105-6263

VL - 9

SP - 381

EP - 392

JO - International Journal of Andrology

JF - International Journal of Andrology

IS - 5

ER -

Induced hyperprolactinaemia does not alter FSH binding or ABP secretion in the rat testis

Abstract

UN SDGs

Keywords

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