Potentialities of graphene and its allied derivatives to combat against SARS-CoV-2 infection

Ayesha Hashmi, Vanya Nayak, Kshitij RB Singh, Bhawana Jain, Mitisha Baid, Frank Alexis, Ajaya Kumar Singh

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Graphene is a two-dimensional material with sp2 hybridization that has found its broad-spectrum potentialities in various domains like electronics, robotics, aeronautics, etc.; it has recently gained its utilities in the biomedical domain. The unique properties of graphene and its derivatives of graphene have helped them find their utilities in the biomedical domain. Additionally, the sudden outbreak of SARS-CoV-2 has immensely expanded the research field, which has also benefitted graphene and its derivatives. Currently, the world is facing a global pandemic due to the sudden outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), also known as COVID-19, from its major onset in Wuhan city, China, in December 2019. Presently, many new variants and mutants appear, which is more harmful than previous strains. However, researchers and scientists are focused on understanding the target structure of coronavirus, mechanism, causes and transmission mode, treatment, and alternatives to cure these diseases in this critical pandemic situation; many findings are achieved, but much more is unknown and pending to be explored. This review paper is dedicated to exploring the utilities of graphene and its derivatives in combating the SARS-CoV-2 by highlighting their mechanism and applications in the fabrication of biosensors, personal protection equipment (PPE) kits, 3-D printing, and antiviral coatings. Further, the paper also covers the cytotoxicity caused by graphene and its derivatives and highlights the graphene-based derivatives market aspects in biomedical domains. Thus, graphene and graphene-derived materials are our new hope in this pandemic time, and this review helps acquire broad knowledge about them.

Original languageEnglish
Article number100208
JournalMaterials Today Advances
Volume13
DOIs
StatePublished - Mar 2022

Keywords

  • Applications
  • COVID-19 pandemic
  • Cytotoxicity
  • Graphene oxide (GO)
  • Graphene-based derivatives
  • Nanotechnology
  • SARS-CoV-2

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