Strawberry and human health: Effects beyond antioxidant activity

Francesca Giampieri, José M. Alvarez-Suarez, Maurizio Battino

Research output: Contribution to journalReview articlepeer-review

278 Scopus citations


The usefulness of a diet rich in vegetables and fruits on human health has been widely recognized: a high intake of antioxidant and bioactive compounds may in fact play a crucial role in the prevention of several diseases, such as cancer, cardiovascular, neurodegenerative, and other chronic pathologies. The strawberry (Fragaria × ananassa Duch.) possesses a remarkable nutritional composition in terms of micronutrients, such as minerals, vitamin C, and folates, and non-nutrient elements, such as phenolic compounds, that are essential for human health. Although strawberry phenolics are known mainly for their anti-inflammatory and antioxidant actions, recent studies have demonstrated that their biological activities also spread to other pathways involved in cellular metabolism and cellular survival. This paper has the main objective of reviewing current information about the potential mechanisms involved in the effects elicited by strawberry polyphenols on human health, devoting special attention to the latest findings.

Original languageEnglish
Pages (from-to)3867-3876
Number of pages10
JournalJournal of Agricultural and Food Chemistry
Issue number18
StatePublished - 7 May 2014
Externally publishedYes


  • antioxidant capacity
  • cell signaling modulation
  • epigenetic regulation
  • polyphenols
  • strawberry


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