Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract

Araceli Granja Alvear; Nayely Pineda-Aguilar; Patricia Lozano; Cristóbal Lárez-Velázquez; Gottfried Suppan; Salomé Galeas; Alexis Debut; Karla Vizuete; Lola De Lima; Juan Pablo Saucedo-Vázquez; Frank Alexis; Floralba López

doi:10.3390/bioengineering11050517

Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract

Araceli Granja Alvear
, Nayely Pineda-Aguilar
, Patricia Lozano
, Cristóbal Lárez-Velázquez
, Gottfried Suppan
, Salomé Galeas
, Alexis Debut
, Karla Vizuete
, Lola De Lima
, Juan Pablo Saucedo-Vázquez
, Frank Alexis^*
, Floralba López^*

^*Corresponding author for this work

Universidad Yachay Tech
Centro de Investigación de Materiales Avanzados CIMAV-Monterrey
Benemerita Universidad Autonoma de Puebla
Universidad de Los Andes (ULA)
Escuela Politecnica Nacional
Universidad de las Fuerzas Armadas ESPE

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Synthesis of silver nanoparticles with antibacterial properties using a one-pot green approach that harnesses the natural reducing and capping properties of cinnamon (Cinnamomum verum) bark extract is presented in this work. Silver nitrate was the sole chemical reagent employed in this process, acting as the precursor salt. Gas Chromatography-Mass Spectroscopy (GC-MS), High-Performance Liquid Chromatography (HPLC) analysis, and some phytochemical tests demonstrated that cinnamaldehyde is the main component in the cinnamon bark extract. The resulting bio-reduced silver nanoparticles underwent comprehensive characterization by Ultraviolet–Vis (UV-Vis) and Fourier Transform InfraRed spectrophotometry (FTIR), Dynamic Light Scattering (DLS), Transmission Electron Microscopy, and Scanning Electron Microscopy suggesting that cinnamaldehyde was chemically oxidated to produce silver nanoparticles. These cinnamon-extract-based silver nanoparticles (AgNPs-cinnamon) displayed diverse morphologies ranging from spherical to prismatic shapes, with sizes spanning between 2.94 and 65.1 nm. Subsequently, the antibacterial efficacy of these nanoparticles was investigated against Klebsiella, E. Coli, Pseudomonas, Staphylococcus aureus, and Acinetobacter strains. The results suggest the promising potential of silver nanoparticles obtained (AgNPs-cinnamon) as antimicrobial agents, offering a new avenue in the fight against bacterial infections.

Original language	English
Article number	517
Journal	Bioengineering
Volume	11
Issue number	5
DOIs	https://doi.org/10.3390/bioengineering11050517
State	Published - May 2024

Keywords

antibacterial properties
cinnamaldehyde
green synthesis
nanomaterials
silver nanoparticles

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10.3390/bioengineering11050517

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Granja Alvear, A., Pineda-Aguilar, N., Lozano, P., Lárez-Velázquez, C., Suppan, G., Galeas, S., Debut, A., Vizuete, K., De Lima, L., Saucedo-Vázquez, J. P., Alexis, F., & López, F. (2024). Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract. Bioengineering, 11(5), Article 517. https://doi.org/10.3390/bioengineering11050517

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title = "Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract",

abstract = "Synthesis of silver nanoparticles with antibacterial properties using a one-pot green approach that harnesses the natural reducing and capping properties of cinnamon (Cinnamomum verum) bark extract is presented in this work. Silver nitrate was the sole chemical reagent employed in this process, acting as the precursor salt. Gas Chromatography-Mass Spectroscopy (GC-MS), High-Performance Liquid Chromatography (HPLC) analysis, and some phytochemical tests demonstrated that cinnamaldehyde is the main component in the cinnamon bark extract. The resulting bio-reduced silver nanoparticles underwent comprehensive characterization by Ultraviolet–Vis (UV-Vis) and Fourier Transform InfraRed spectrophotometry (FTIR), Dynamic Light Scattering (DLS), Transmission Electron Microscopy, and Scanning Electron Microscopy suggesting that cinnamaldehyde was chemically oxidated to produce silver nanoparticles. These cinnamon-extract-based silver nanoparticles (AgNPs-cinnamon) displayed diverse morphologies ranging from spherical to prismatic shapes, with sizes spanning between 2.94 and 65.1 nm. Subsequently, the antibacterial efficacy of these nanoparticles was investigated against Klebsiella, E. Coli, Pseudomonas, Staphylococcus aureus, and Acinetobacter strains. The results suggest the promising potential of silver nanoparticles obtained (AgNPs-cinnamon) as antimicrobial agents, offering a new avenue in the fight against bacterial infections.",

keywords = "antibacterial properties, cinnamaldehyde, green synthesis, nanomaterials, silver nanoparticles",

author = "\{Granja Alvear\}, Araceli and Nayely Pineda-Aguilar and Patricia Lozano and Crist{\'o}bal L{\'a}rez-Vel{\'a}zquez and Gottfried Suppan and Salom{\'e} Galeas and Alexis Debut and Karla Vizuete and \{De Lima\}, Lola and Saucedo-V{\'a}zquez, \{Juan Pablo\} and Frank Alexis and Floralba L{\'o}pez",

note = "Publisher Copyright: {\textcopyright} 2024 by the authors.",

year = "2024",

month = may,

doi = "10.3390/bioengineering11050517",

language = "Ingl{\'e}s",

volume = "11",

journal = "Bioengineering",

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Granja Alvear, A, Pineda-Aguilar, N, Lozano, P, Lárez-Velázquez, C, Suppan, G, Galeas, S, Debut, A, Vizuete, K, De Lima, L, Saucedo-Vázquez, JP, Alexis, F & López, F 2024, 'Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract', Bioengineering, vol. 11, no. 5, 517. https://doi.org/10.3390/bioengineering11050517

TY - JOUR

T1 - Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract

AU - Granja Alvear, Araceli

AU - Pineda-Aguilar, Nayely

AU - Lozano, Patricia

AU - Lárez-Velázquez, Cristóbal

AU - Suppan, Gottfried

AU - Galeas, Salomé

AU - Debut, Alexis

AU - Vizuete, Karla

AU - De Lima, Lola

AU - Saucedo-Vázquez, Juan Pablo

AU - Alexis, Frank

AU - López, Floralba

PY - 2024/5

Y1 - 2024/5

N2 - Synthesis of silver nanoparticles with antibacterial properties using a one-pot green approach that harnesses the natural reducing and capping properties of cinnamon (Cinnamomum verum) bark extract is presented in this work. Silver nitrate was the sole chemical reagent employed in this process, acting as the precursor salt. Gas Chromatography-Mass Spectroscopy (GC-MS), High-Performance Liquid Chromatography (HPLC) analysis, and some phytochemical tests demonstrated that cinnamaldehyde is the main component in the cinnamon bark extract. The resulting bio-reduced silver nanoparticles underwent comprehensive characterization by Ultraviolet–Vis (UV-Vis) and Fourier Transform InfraRed spectrophotometry (FTIR), Dynamic Light Scattering (DLS), Transmission Electron Microscopy, and Scanning Electron Microscopy suggesting that cinnamaldehyde was chemically oxidated to produce silver nanoparticles. These cinnamon-extract-based silver nanoparticles (AgNPs-cinnamon) displayed diverse morphologies ranging from spherical to prismatic shapes, with sizes spanning between 2.94 and 65.1 nm. Subsequently, the antibacterial efficacy of these nanoparticles was investigated against Klebsiella, E. Coli, Pseudomonas, Staphylococcus aureus, and Acinetobacter strains. The results suggest the promising potential of silver nanoparticles obtained (AgNPs-cinnamon) as antimicrobial agents, offering a new avenue in the fight against bacterial infections.

AB - Synthesis of silver nanoparticles with antibacterial properties using a one-pot green approach that harnesses the natural reducing and capping properties of cinnamon (Cinnamomum verum) bark extract is presented in this work. Silver nitrate was the sole chemical reagent employed in this process, acting as the precursor salt. Gas Chromatography-Mass Spectroscopy (GC-MS), High-Performance Liquid Chromatography (HPLC) analysis, and some phytochemical tests demonstrated that cinnamaldehyde is the main component in the cinnamon bark extract. The resulting bio-reduced silver nanoparticles underwent comprehensive characterization by Ultraviolet–Vis (UV-Vis) and Fourier Transform InfraRed spectrophotometry (FTIR), Dynamic Light Scattering (DLS), Transmission Electron Microscopy, and Scanning Electron Microscopy suggesting that cinnamaldehyde was chemically oxidated to produce silver nanoparticles. These cinnamon-extract-based silver nanoparticles (AgNPs-cinnamon) displayed diverse morphologies ranging from spherical to prismatic shapes, with sizes spanning between 2.94 and 65.1 nm. Subsequently, the antibacterial efficacy of these nanoparticles was investigated against Klebsiella, E. Coli, Pseudomonas, Staphylococcus aureus, and Acinetobacter strains. The results suggest the promising potential of silver nanoparticles obtained (AgNPs-cinnamon) as antimicrobial agents, offering a new avenue in the fight against bacterial infections.

KW - antibacterial properties

KW - cinnamaldehyde

KW - green synthesis

KW - nanomaterials

KW - silver nanoparticles

UR - https://www.scopus.com/pages/publications/85194096692

U2 - 10.3390/bioengineering11050517

DO - 10.3390/bioengineering11050517

M3 - Artículo

AN - SCOPUS:85194096692

SN - 2306-5354

VL - 11

JO - Bioengineering

JF - Bioengineering

IS - 5

M1 - 517

ER -

Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract

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Keywords

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