Targeted nanoparticles for cancer therapy

Frank X. Gu; Rohit Karnik; Andrew Z. Wang; Frank Alexis; Etgar Levy-Nissenbaum; Seungpyo Hong; Robert S. Langer; Omid C. Farokhzad

doi:10.1016/S1748-0132(07)70083-X

Targeted nanoparticles for cancer therapy

Frank X. Gu^*
, Rohit Karnik
, Andrew Z. Wang
, Frank Alexis
, Etgar Levy-Nissenbaum
, Seungpyo Hong
, Robert S. Langer
, Omid C. Farokhzad

^*Corresponding author for this work

Massachusetts Institute of Technology
Massachusetts Institute of Technology
Brigham and Women's Hospital

Research output: Contribution to journal › Article › peer-review

569 Scopus citations

Abstract

Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.

Original language	English
Pages (from-to)	14-21
Number of pages	8
Journal	Nano Today
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/S1748-0132(07)70083-X
State	Published - Jun 2007
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/S1748-0132(07)70083-X

Cite this

@article{1efb8869dcdb42d8ac6fab6b52cbabcc,

title = "Targeted nanoparticles for cancer therapy",

abstract = "Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.",

author = "Gu, \{Frank X.\} and Rohit Karnik and Wang, \{Andrew Z.\} and Frank Alexis and Etgar Levy-Nissenbaum and Seungpyo Hong and Langer, \{Robert S.\} and Farokhzad, \{Omid C.\}",

year = "2007",

month = jun,

doi = "10.1016/S1748-0132(07)70083-X",

language = "Ingl{\'e}s",

volume = "2",

pages = "14--21",

journal = "Nano Today",

issn = "1748-0132",

publisher = "Elsevier B.V.",

number = "3",

}

TY - JOUR

T1 - Targeted nanoparticles for cancer therapy

AU - Gu, Frank X.

AU - Karnik, Rohit

AU - Wang, Andrew Z.

AU - Alexis, Frank

AU - Levy-Nissenbaum, Etgar

AU - Hong, Seungpyo

AU - Langer, Robert S.

AU - Farokhzad, Omid C.

PY - 2007/6

Y1 - 2007/6

N2 - Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.

AB - Over the past decade, there has been an increasing interest in using nanotechnology for cancer therapy. The development of smart targeted nanoparticles (NPs) that can deliver drugs at a sustained rate directly to cancer cells may provide better efficacy and lower toxicity for treating primary and advanced metastatic tumors. We highlight some of the promising classes of targeting molecules that are under development for the delivery of NPs. We also review the emerging technologies for the fabrication of targeted NPs using microfluidic devices.

UR - https://www.scopus.com/pages/publications/34247642609

U2 - 10.1016/S1748-0132(07)70083-X

DO - 10.1016/S1748-0132(07)70083-X

M3 - Artículo

AN - SCOPUS:34247642609

SN - 1748-0132

VL - 2

SP - 14

EP - 21

JO - Nano Today

JF - Nano Today

IS - 3

ER -

Targeted nanoparticles for cancer therapy

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this