The origin of human pathogens

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Modern human infectious diseases are thought to have originated in domestic animals during the Neolithic period or afterwards. However, recent genetic, phylogeographic and molecular clock analyses of microbial genomes point to a much older Paleolithic origin (2.5 million to 10,000 years ago) and suggest that many of these pathogens coevolved with ancestral hominids in Africa. Another group of human pathogens seems to have derived recently from non-human hominids.

Original languageEnglish
Title of host publicationConfronting Emerging Zoonoses
Subtitle of host publicationThe One Health Paradigm
PublisherSpringer Japan
Number of pages9
ISBN (Electronic)9784431551201
ISBN (Print)4431551190, 9784431551195
StatePublished - 1 Jun 2014


  • Evolution
  • Molecular clock
  • Phylogeny
  • Zoonosis


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