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The preventive and inhibitory effects of red raspberries on cancer

  • Zexiu Qi
  • , Bei Yang
  • , Francesca Giampieri
  • , Danila Cianciosi
  • , José Miguel Alvarez-Suarez
  • , Maria Elexpuru-Zabaleta
  • , Josè L. Quiles
  • , Tamara Y. Forbes-Hernandez
  • , Di Zhang
  • , Weibin Bai
  • , Lingmin Tian
  • , Bruno Mezzetti
  • , Maurizio Battino
  • , Yasmany Armas Diaz*
  • *Corresponding author for this work
  • Universita Politecnica Delle Marche
  • Universidad Europea Del Atlántico (UEA)
  • University of Granada
  • Jiangsu University
  • Guangdong Engineering Technology Center of Food Safety

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Red raspberries are gaining attention more and more for their nutritional and bioactive components, with potential health effects such as antitumor properties. This review aims to describe the antioxidant activities of red raspberries, emphasizing the role of anthocyanins and ellagitannins as primary contributors among red raspberry polyphenols; it also outlined the connection between red raspberries and their role in inhibiting cancer cell growth by regulating oxidative stress. Numerous studies suggest that red raspberries are able to block cancer cell progression by inhibiting proliferation, migration, and autophagy, as well as regulating the cell cycle, angiogenesis, and DNA damage repair. This review sheds light to the growing evidence supporting antioxidants as a crucial link between fruit consumption and cancer prevention.

Original languageEnglish
Pages (from-to)61-71
Number of pages11
JournalJournal of Berry Research
Volume14
Issue number1
DOIs
StatePublished - 19 Mar 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Red raspberry
  • anthocyanins
  • cancer
  • ellagitannins
  • oxidative stress

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