TY - JOUR
T1 - A closer look to polyesters
T2 - Properties, synthesis, characterization, and particle drug delivery applications
AU - Viteri, Katherine Pazmiño
AU - Vizuete, Karla Sofía
AU - Alexis, Frank
AU - Kumar, Brajesh
AU - Debut, Alexis
N1 - Publisher Copyright:
© 2021 Bentham Science Publishers.
PY - 2021
Y1 - 2021
N2 - Background: Natural and synthetic polymeric materials can be used in the fields of bio-medicine and pharmaceuticals as a material for controlled drug delivery. Among the synthetic poly-mers, polyesters are synthesized from two natural monomers: lactic and glycolic acid, which are bio-compatible and biodegradable. Objective: Here, we review broad aspects of polyesters including its properties, synthesis, characteri-zation, and particle drug delivery applications. Conclusion: Finally, we have concluded that polyesters are certainly very versatile material that are continuously reinvented for future application in new areas of science and medicine. However, sev-eral aspects must be considered when synthesizing polyesters, which have a direct influence on bio-degradability and biocompatibility. These properties may limit the performance of in vitro and in vi-vo tests.
AB - Background: Natural and synthetic polymeric materials can be used in the fields of bio-medicine and pharmaceuticals as a material for controlled drug delivery. Among the synthetic poly-mers, polyesters are synthesized from two natural monomers: lactic and glycolic acid, which are bio-compatible and biodegradable. Objective: Here, we review broad aspects of polyesters including its properties, synthesis, characteri-zation, and particle drug delivery applications. Conclusion: Finally, we have concluded that polyesters are certainly very versatile material that are continuously reinvented for future application in new areas of science and medicine. However, sev-eral aspects must be considered when synthesizing polyesters, which have a direct influence on bio-degradability and biocompatibility. These properties may limit the performance of in vitro and in vi-vo tests.
KW - Biodegradable
KW - Drug delivery
KW - Microparticles
KW - Nanoparticles
KW - Polyesters
KW - Polymers
UR - http://www.scopus.com/inward/record.url?scp=85118396097&partnerID=8YFLogxK
U2 - 10.2174/2210681210999201124155313
DO - 10.2174/2210681210999201124155313
M3 - Artículo de revisión
AN - SCOPUS:85118396097
SN - 2210-6812
VL - 11
JO - Nanoscience and Nanotechnology - Asia
JF - Nanoscience and Nanotechnology - Asia
IS - 5
M1 - e241120188332
ER -