Batería neurofisiológica para la neuromonitorización del coma y el diagnóstico de la muerte encefálica

Calixto Machado Curbelo, Liana Portela Hernández, Maria G. García Roca, Jesús Pérez Nellar, Claudio E. Scherle Matamoros

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

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Resumen

Authors reviewed on application of multimodality evoked potentials (MEP) for coma neuromonitoring and as confirmatory tests in brain death (BD) diagnosis. Results presented demonstrate the MEPs value in forecast of evolution course of comatose patients, allowing prediction of brain function deterioration and thus, physician may take early therapeutic measures before establishment of irreversible brain lesions. The high time resolution of these tests allows an early detection of bran function changes, making them suitable for neuromonitoring of critical patients. In relation to MEPs and the electroretinogram (ERG) application, as confirmatory tests in the diagnosis of BD, characteristic electrophysiological patterns are found showing a lack of sensorial conduction in three different pathways within the skull. However, when considering a confirmatory test battery but not as isolated techniques, it is possible to optimize the electrophysiological study and to increase diagnostic reliability. By other hand, due to MEPs and ERG resistance to hypothermia, to use of barbiturates, to anesthetics, to intoxications from different drugs, to anoxia, etc, it is possible to apply such test battery in decreasing observation time required to establish the definite diagnosis of BD, and to confirm this diagnosis in clinical circumstances that make difficult this diagnostic procedure.

Título traducido de la contribuciónNeurophysiologic test battery for neuromonitoring of comatose patients and brain death diagnosis
Idioma originalEspañol
PublicaciónRevista Cubana de Medicina
Volumen48
N.º2
EstadoPublicada - 2009
Publicado de forma externa

Palabras clave

  • Brain death
  • Coma
  • Electroretinogram
  • Multimodality evoked potentials
  • Neuromonitoring

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