Biomedical applications of hydroxyapatite nanoparticles

S. C.J. Loo, T. Moore, B. Banik, F. Alexis

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

92 Citas (Scopus)

Resumen

Nanotechnologies have the potential to improve current disease diagnosis due to their ability to circulate in the blood and distribute in the body to image tissues and cells or therapeutical applications to deliver a payload. Among nanoparticles with different materials composition, inorganic nanoparticles composed of calcium phosphate have numerous advantages including ease of synthesis, control of physico-chemical properties, strong interactions with their payload, and biocompatibility. In this review we discuss the different routes of synthesis of calcium phosphate nanoparticles, novel systems, strategies to load agents, biostability and cytotoxicity, biodistribution and pharmacokinetics, bio-imaging and therapeutical applications.

Idioma originalInglés
Páginas (desde-hasta)333-342
Número de páginas10
PublicaciónCurrent Pharmaceutical Biotechnology
Volumen11
N.º4
DOI
EstadoPublicada - 2010
Publicado de forma externa

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