Cognitive and affective correlates of temperament in Parkinson's disease

Graham Pluck, Richard G. Brown

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

7 Citas (Scopus)


Parkinson's disease (PD) patients display low novelty seeking scores on the Tridimensional Personality Questionnaire (TPQ), which may reflect the low dopamine function that characterises the disease. People with PD also display raised harm avoidance scores. Due to these and other observations, a "parkinsonian personality" has been suggested. However, little is known about how these features relate to cognitive and affective disorders, which are also common in PD. We examined links between TPQ scores and performance on an attentional orienting task in a sample of 20 people with PD. In addition, associations between TPQ and depression and anxiety scores were explored. It was found that novelty seeking scores were significantly correlated with a reaction time measure of attentional orienting to visual novelty. Harm avoidance scores were significantly correlated with anxiety, but not depression scores. These findings extend our understanding of how temperament interacts with cognitive and affective features of the disorder.

Idioma originalInglés
Número de artículo893873
PublicaciónDepression Research and Treatment
EstadoPublicada - 2011
Publicado de forma externa


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