Facial morphometry of Ecuadorian patients with growth hormone receptor deficiency/Laron syndrome

G. B. Schaefer; A. L. Rosenbloom; J. Guevara-Aguirre; E. A. Campbell; F. Ullrich; K. Patil; J. L. Frias

doi:10.1136/jmg.31.8.635

Facial morphometry of Ecuadorian patients with growth hormone receptor deficiency/Laron syndrome

G. B. Schaefer, A. L. Rosenbloom, J. Guevara-Aguirre, E. A. Campbell, F. Ullrich, K. Patil, J. L. Frias

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34 Citas (Scopus)

Resumen

Facial morphometry using computerised image analysis was performed on patients with growth hormone receptor deficiency (Laron syndrome) from an inbred population of southern Ecuador. Morphometrics were compared for 49 patients, 70 unaffected relatives, and 14 unrelated persons. Patients with growth hormone receptor deficiency showed significant decreases in measures of vertical facial growth as compared to unaffected relatives and unrelated persons with short stature from other causes. This report validates and quantifies the clinical impression of foreshortened facies in growth hormone receptor deficiency.

Idioma original	Inglés
Páginas (desde-hasta)	635-639
Número de páginas	5
Publicación	Journal of Medical Genetics
Volumen	31
N.º	8
DOI	https://doi.org/10.1136/jmg.31.8.635
Estado	Publicada - ago. 1994
Publicado de forma externa	Sí

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abstract = "Facial morphometry using computerised image analysis was performed on patients with growth hormone receptor deficiency (Laron syndrome) from an inbred population of southern Ecuador. Morphometrics were compared for 49 patients, 70 unaffected relatives, and 14 unrelated persons. Patients with growth hormone receptor deficiency showed significant decreases in measures of vertical facial growth as compared to unaffected relatives and unrelated persons with short stature from other causes. This report validates and quantifies the clinical impression of foreshortened facies in growth hormone receptor deficiency.",

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AU - Rosenbloom, A. L.

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AU - Campbell, E. A.

AU - Ullrich, F.

AU - Patil, K.

AU - Frias, J. L.

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N2 - Facial morphometry using computerised image analysis was performed on patients with growth hormone receptor deficiency (Laron syndrome) from an inbred population of southern Ecuador. Morphometrics were compared for 49 patients, 70 unaffected relatives, and 14 unrelated persons. Patients with growth hormone receptor deficiency showed significant decreases in measures of vertical facial growth as compared to unaffected relatives and unrelated persons with short stature from other causes. This report validates and quantifies the clinical impression of foreshortened facies in growth hormone receptor deficiency.

AB - Facial morphometry using computerised image analysis was performed on patients with growth hormone receptor deficiency (Laron syndrome) from an inbred population of southern Ecuador. Morphometrics were compared for 49 patients, 70 unaffected relatives, and 14 unrelated persons. Patients with growth hormone receptor deficiency showed significant decreases in measures of vertical facial growth as compared to unaffected relatives and unrelated persons with short stature from other causes. This report validates and quantifies the clinical impression of foreshortened facies in growth hormone receptor deficiency.

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JO - Journal of Medical Genetics

JF - Journal of Medical Genetics

IS - 8

ER -

Facial morphometry of Ecuadorian patients with growth hormone receptor deficiency/Laron syndrome

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