First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador

J. C. Fernandez-Cadena; M. Carvajal; E. Muñoz; B. Prado-Vivar; S. Marquez; S. Proaño; R. Bayas; J. J. Guadalupe; M. Becerra-Wong; B. Gutierrez; G. Morey-Leon; G. Trueba; M. Grunauer; V. Barragán; P. Rojas-Silva; D. Andrade-Molina; P. Cárdenas

doi:10.1016/j.nmni.2022.101001

First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador

J. C. Fernandez-Cadena, M. Carvajal, E. Muñoz, B. Prado-Vivar, S. Marquez, S. Proaño, R. Bayas, J. J. Guadalupe, M. Becerra-Wong, B. Gutierrez, G. Morey-Leon, G. Trueba, M. Grunauer, V. Barragán, P. Rojas-Silva, D. Andrade-Molina, P. Cárdenas

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

Resumen

Background: COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported. Methodology: A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in NextClade and Pangolin webservers, and considering the genotyping findings, conflicting results were obtained. Results: The raw data of the sequencing was analyzed, and nucleotide variants were identified between different reads of the virus genome. B.1 and P.1 lineages were identified within the same sample. Conclusions: We concluded that this is a co-infection case with two SARS-CoV-2 lineages, the first one reported in Ecuador.

Idioma original	Inglés
Número de artículo	101001
Publicación	New Microbes and New Infections
Volumen	48
DOI	https://doi.org/10.1016/j.nmni.2022.101001
Estado	Publicada - jul. 2022

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Acceder al documento

10.1016/j.nmni.2022.101001

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

Fernandez-Cadena, J. C., Carvajal, M., Muñoz, E., Prado-Vivar, B., Marquez, S., Proaño, S., Bayas, R., Guadalupe, J. J., Becerra-Wong, M., Gutierrez, B., Morey-Leon, G., Trueba, G., Grunauer, M., Barragán, V., Rojas-Silva, P., Andrade-Molina, D., & Cárdenas, P. (2022). First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador. New Microbes and New Infections, 48, Artículo 101001. https://doi.org/10.1016/j.nmni.2022.101001

@article{ef91fa1204164f968804358f6d720dab,

title = "First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador",

abstract = "Background: COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported. Methodology: A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in NextClade and Pangolin webservers, and considering the genotyping findings, conflicting results were obtained. Results: The raw data of the sequencing was analyzed, and nucleotide variants were identified between different reads of the virus genome. B.1 and P.1 lineages were identified within the same sample. Conclusions: We concluded that this is a co-infection case with two SARS-CoV-2 lineages, the first one reported in Ecuador.",

keywords = "COVID19, NGS, SARS-CoV-2, co-infection, genome sequencing",

author = "Fernandez-Cadena, {J. C.} and M. Carvajal and E. Mu{\~n}oz and B. Prado-Vivar and S. Marquez and S. Proa{\~n}o and R. Bayas and Guadalupe, {J. J.} and M. Becerra-Wong and B. Gutierrez and G. Morey-Leon and G. Trueba and M. Grunauer and V. Barrag{\'a}n and P. Rojas-Silva and D. Andrade-Molina and P. C{\'a}rdenas",

note = "Publisher Copyright: {\textcopyright} 2022 The Author(s)",

year = "2022",

month = jul,

doi = "10.1016/j.nmni.2022.101001",

language = "Ingl{\'e}s",

volume = "48",

journal = "New Microbes and New Infections",

issn = "2052-2975",

}

Fernandez-Cadena, JC, Carvajal, M, Muñoz, E, Prado-Vivar, B, Marquez, S, Proaño, S, Bayas, R, Guadalupe, JJ, Becerra-Wong, M, Gutierrez, B, Morey-Leon, G, Trueba, G , Grunauer, M , Barragán, V , Rojas-Silva, P, Andrade-Molina, D & Cárdenas, P 2022, 'First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador', New Microbes and New Infections, vol. 48, 101001. https://doi.org/10.1016/j.nmni.2022.101001

TY - JOUR

T1 - First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador

AU - Fernandez-Cadena, J. C.

AU - Carvajal, M.

AU - Muñoz, E.

AU - Prado-Vivar, B.

AU - Marquez, S.

AU - Proaño, S.

AU - Bayas, R.

AU - Guadalupe, J. J.

AU - Becerra-Wong, M.

AU - Gutierrez, B.

AU - Morey-Leon, G.

AU - Trueba, G.

AU - Grunauer, M.

AU - Barragán, V.

AU - Rojas-Silva, P.

AU - Andrade-Molina, D.

AU - Cárdenas, P.

PY - 2022/7

Y1 - 2022/7

N2 - Background: COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported. Methodology: A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in NextClade and Pangolin webservers, and considering the genotyping findings, conflicting results were obtained. Results: The raw data of the sequencing was analyzed, and nucleotide variants were identified between different reads of the virus genome. B.1 and P.1 lineages were identified within the same sample. Conclusions: We concluded that this is a co-infection case with two SARS-CoV-2 lineages, the first one reported in Ecuador.

AB - Background: COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported. Methodology: A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in NextClade and Pangolin webservers, and considering the genotyping findings, conflicting results were obtained. Results: The raw data of the sequencing was analyzed, and nucleotide variants were identified between different reads of the virus genome. B.1 and P.1 lineages were identified within the same sample. Conclusions: We concluded that this is a co-infection case with two SARS-CoV-2 lineages, the first one reported in Ecuador.

KW - COVID19

KW - NGS

KW - SARS-CoV-2

KW - co-infection

KW - genome sequencing

UR - http://www.scopus.com/inward/record.url?scp=85138440963&partnerID=8YFLogxK

U2 - 10.1016/j.nmni.2022.101001

DO - 10.1016/j.nmni.2022.101001

M3 - Artículo

AN - SCOPUS:85138440963

SN - 2052-2975

VL - 48

JO - New Microbes and New Infections

JF - New Microbes and New Infections

M1 - 101001

ER -

First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador

Resumen

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto