TY - JOUR
T1 - High prevalence of enteroinvasive Escherichia coli isolated in a remote region of northern coastal Ecuador
AU - Vieira, Nadia
AU - Bates, Sarah J.
AU - Solberg, Owen D.
AU - Ponce, Karina
AU - Howsmon, Rebecca
AU - Cevallos, William
AU - Trueba, Gabriel
AU - Riley, Lee
AU - Eisenberg, Joseph N.S.
PY - 2007/3
Y1 - 2007/3
N2 - Enteroinvasive Escherichia coli (EIEC) causes dysentery; however, it is less widely reported than other etiological agents in studies of diarrhea worldwide. Between August 2003 and July 2005, stool samples were collected in case-control studies in 22 rural communities in northwestern Ecuador. Infection was assessed by PCR specific for LT and STa genes of enterotoxigenic E. coli (ETEC), the bfp gene of enteropathogenic E. coli (EPEC), and the ipaH gene of both enteroinvasive E. coli and Shigellae. The pathogenic E. coli most frequently identified were EIEC (3.2 cases/100 persons) and Shigellae (1.5 cases/100 persons), followed by ETEC (1.3 cases/100 persons), and EPEC (0.9 case/100 persons). EIEC exhibited similar risk-factor relationships with other pathotypes analyzed but different age-specific infection rates. EIEC was the predominant diarrheagenic bacteria isolated in our community-based study, a unique observation compared with other regions of the world.
AB - Enteroinvasive Escherichia coli (EIEC) causes dysentery; however, it is less widely reported than other etiological agents in studies of diarrhea worldwide. Between August 2003 and July 2005, stool samples were collected in case-control studies in 22 rural communities in northwestern Ecuador. Infection was assessed by PCR specific for LT and STa genes of enterotoxigenic E. coli (ETEC), the bfp gene of enteropathogenic E. coli (EPEC), and the ipaH gene of both enteroinvasive E. coli and Shigellae. The pathogenic E. coli most frequently identified were EIEC (3.2 cases/100 persons) and Shigellae (1.5 cases/100 persons), followed by ETEC (1.3 cases/100 persons), and EPEC (0.9 case/100 persons). EIEC exhibited similar risk-factor relationships with other pathotypes analyzed but different age-specific infection rates. EIEC was the predominant diarrheagenic bacteria isolated in our community-based study, a unique observation compared with other regions of the world.
UR - http://www.scopus.com/inward/record.url?scp=34247150308&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.2007.76.528
DO - 10.4269/ajtmh.2007.76.528
M3 - Artículo
C2 - 17360879
AN - SCOPUS:34247150308
SN - 0002-9637
VL - 76
SP - 528
EP - 533
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 3
ER -
