International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19

Verena Börger; Daniel J. Weiss; Johnathon D. Anderson; Francesc E. Borràs; Benedetta Bussolati; David R.F. Carter; Massimo Dominici; Juan M. Falcón-Pérez; Mario Gimona; Andrew F. Hill; Andrew M. Hoffman; Dominique de Kleijn; Bruce L. Levine; Rebecca Lim; Jan Lötvall; S. Alex Mitsialis; Marta Monguió-Tortajada; Maurizio Muraca; Rienk Nieuwland; Anna Nowocin; Lorraine O'Driscoll; Luis A. Ortiz; Donald G. Phinney; Ilona Reischl; Eva Rohde; Ralf Sanzenbacher; Clotilde Théry; Wei Seong Toh; Kenneth W. Witwer; Sai Kiang Lim; Bernd Giebel

doi:10.1016/j.jcyt.2020.05.002

International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19

Verena Börger
, Daniel J. Weiss
, Johnathon D. Anderson
, Francesc E. Borràs
, Benedetta Bussolati
, David R.F. Carter
, Massimo Dominici
, Juan M. Falcón-Pérez
, Mario Gimona
, Andrew F. Hill
, Andrew M. Hoffman
, Dominique de Kleijn
, Bruce L. Levine
, Rebecca Lim
, Jan Lötvall
, S. Alex Mitsialis
, Marta Monguió-Tortajada
, Maurizio Muraca
, Rienk Nieuwland
, Anna Nowocin

Lorraine O'Driscoll, Luis A. Ortiz, Donald G. Phinney, Ilona Reischl, Eva Rohde, Ralf Sanzenbacher, Clotilde Théry, Wei Seong Toh, Kenneth W. Witwer^*, Sai Kiang Lim^*, Bernd Giebel^*

^*Autor correspondiente de este trabajo

University of Duisburg-Essen
University of Vermont
University of California at Davis
Hospital Universitari Germans Trias i Pujol
Université di Torino
Oxford Brookes University
University of Modena and Reggio Emilia
CIC BioGUNE
Centro de Investigación Biomédica en Red: Enfermedades Hepáticas y Digestivas (CIBERehd)
Ikerbasque Basque Foundation for Science
Paracelsus Private Medical University
La Trobe University
University of Pennsylvania School of Veterinary Medicine
University Medical Center Utrecht
University of Pennsylvania
Monash University
University of Gothenburg
Boston Children's Hospital
University of Padua
Amsterdam University Medical Centers
Medicines and Healthcare Products Regulatory Agency
The NatPro Centre. Trinity College Dublin
University of Pittsburgh
University of Florida
Austrian Agency for Health and Food Safety GmbH
Salzburger Landeskliniken
Paul-Ehrlich-Institut
Université PSL
National University of Singapore
Johns Hopkins University
Agency for Science, Technology and Research, Singapore

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112 Citas (Scopus)

Resumen

STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments for COVID-19. Research and trials in this area are encouraged. However, ISEV and ISCT do not currently endorse the use of EVs or exosomes for any purpose in COVID-19, including but not limited to reducing cytokine storm, exerting regenerative effects or delivering drugs, pending the generation of appropriate manufacturing and quality control provisions, pre-clinical safety and efficacy data, rational clinical trial design and proper regulatory oversight.

Idioma original	Inglés
Páginas (desde-hasta)	482-485
Número de páginas	4
Publicación	Cytotherapy
Volumen	22
N.º	9
DOI	https://doi.org/10.1016/j.jcyt.2020.05.002
Estado	Publicada - sep. 2020
Publicado de forma externa	Sí

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Börger, V., Weiss, D. J., Anderson, J. D., Borràs, F. E., Bussolati, B., Carter, D. R. F., Dominici, M., Falcón-Pérez, J. M., Gimona, M., Hill, A. F., Hoffman, A. M., de Kleijn, D., Levine, B. L., Lim, R., Lötvall, J., Mitsialis, S. A., Monguió-Tortajada, M., Muraca, M., Nieuwland, R., ... Giebel, B. (2020). International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19. Cytotherapy, 22(9), 482-485. https://doi.org/10.1016/j.jcyt.2020.05.002

Börger, Verena ; Weiss, Daniel J. ; Anderson, Johnathon D. et al. / International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells : considerations for potential therapeutic agents to suppress coronavirus disease-19. En: Cytotherapy. 2020 ; Vol. 22, N.º 9. pp. 482-485.

@article{1819a7432d1f4a8cb3c2ca2641e94e5d,

title = "International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19",

abstract = "STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments for COVID-19. Research and trials in this area are encouraged. However, ISEV and ISCT do not currently endorse the use of EVs or exosomes for any purpose in COVID-19, including but not limited to reducing cytokine storm, exerting regenerative effects or delivering drugs, pending the generation of appropriate manufacturing and quality control provisions, pre-clinical safety and efficacy data, rational clinical trial design and proper regulatory oversight.",

author = "Verena B{\"o}rger and Weiss, \{Daniel J.\} and Anderson, \{Johnathon D.\} and Borr{\`a}s, \{Francesc E.\} and Benedetta Bussolati and Carter, \{David R.F.\} and Massimo Dominici and Falc{\'o}n-P{\'e}rez, \{Juan M.\} and Mario Gimona and Hill, \{Andrew F.\} and Hoffman, \{Andrew M.\} and \{de Kleijn\}, Dominique and Levine, \{Bruce L.\} and Rebecca Lim and Jan L{\"o}tvall and Mitsialis, \{S. Alex\} and Marta Mongui{\'o}-Tortajada and Maurizio Muraca and Rienk Nieuwland and Anna Nowocin and Lorraine O'Driscoll and Ortiz, \{Luis A.\} and Phinney, \{Donald G.\} and Ilona Reischl and Eva Rohde and Ralf Sanzenbacher and Clotilde Th{\'e}ry and Toh, \{Wei Seong\} and Witwer, \{Kenneth W.\} and Lim, \{Sai Kiang\} and Bernd Giebel",

note = "Publisher Copyright: {\textcopyright} 2020 International Society for Cell and Gene Therapy",

year = "2020",

month = sep,

doi = "10.1016/j.jcyt.2020.05.002",

language = "Ingl{\'e}s",

volume = "22",

pages = "482--485",

journal = "Cytotherapy",

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Börger, V, Weiss, DJ, Anderson, JD, Borràs, FE, Bussolati, B, Carter, DRF, Dominici, M, Falcón-Pérez, JM, Gimona, M, Hill, AF, Hoffman, AM, de Kleijn, D, Levine, BL, Lim, R, Lötvall, J, Mitsialis, SA, Monguió-Tortajada, M, Muraca, M, Nieuwland, R, Nowocin, A, O'Driscoll, L, Ortiz, LA, Phinney, DG, Reischl, I, Rohde, E, Sanzenbacher, R, Théry, C, Toh, WS, Witwer, KW, Lim, SK & Giebel, B 2020, 'International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19', Cytotherapy, vol. 22, n.º 9, pp. 482-485. https://doi.org/10.1016/j.jcyt.2020.05.002

International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19. / Börger, Verena; Weiss, Daniel J.; Anderson, Johnathon D. et al.
En: Cytotherapy, Vol. 22, N.º 9, 09.2020, p. 482-485.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

TY - JOUR

T1 - International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells

T2 - considerations for potential therapeutic agents to suppress coronavirus disease-19

AU - Börger, Verena

AU - Weiss, Daniel J.

AU - Anderson, Johnathon D.

AU - Borràs, Francesc E.

AU - Bussolati, Benedetta

AU - Carter, David R.F.

AU - Dominici, Massimo

AU - Falcón-Pérez, Juan M.

AU - Gimona, Mario

AU - Hill, Andrew F.

AU - Hoffman, Andrew M.

AU - de Kleijn, Dominique

AU - Levine, Bruce L.

AU - Lim, Rebecca

AU - Lötvall, Jan

AU - Mitsialis, S. Alex

AU - Monguió-Tortajada, Marta

AU - Muraca, Maurizio

AU - Nieuwland, Rienk

AU - Nowocin, Anna

AU - O'Driscoll, Lorraine

AU - Ortiz, Luis A.

AU - Phinney, Donald G.

AU - Reischl, Ilona

AU - Rohde, Eva

AU - Sanzenbacher, Ralf

AU - Théry, Clotilde

AU - Toh, Wei Seong

AU - Witwer, Kenneth W.

AU - Lim, Sai Kiang

AU - Giebel, Bernd

PY - 2020/9

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AB - STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments for COVID-19. Research and trials in this area are encouraged. However, ISEV and ISCT do not currently endorse the use of EVs or exosomes for any purpose in COVID-19, including but not limited to reducing cytokine storm, exerting regenerative effects or delivering drugs, pending the generation of appropriate manufacturing and quality control provisions, pre-clinical safety and efficacy data, rational clinical trial design and proper regulatory oversight.

UR - https://www.scopus.com/pages/publications/85087294732

U2 - 10.1016/j.jcyt.2020.05.002

DO - 10.1016/j.jcyt.2020.05.002

M3 - Artículo

C2 - 32425691

AN - SCOPUS:85087294732

SN - 1465-3249

VL - 22

SP - 482

EP - 485

JO - Cytotherapy

JF - Cytotherapy

IS - 9

ER -

Börger V, Weiss DJ, Anderson JD, Borràs FE, Bussolati B, Carter DRF et al. International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19. Cytotherapy. 2020 sep.;22(9):482-485. doi: 10.1016/j.jcyt.2020.05.002