Ligand and structure-based discovery of phosphorus-containing compounds as potential metalloproteinase inhibitors

Biochemistry, Genetics and Molecular Biology

• Metalloprotease Inhibitor 100%
• Dynamics 50%
• Active Site 50%
• Quantitative Structure-Activity Relationship 50%
• Enzyme 50%
• Binding Energy 50%
• Thermolysin 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Virtual Screening 100%
• Metalloproteinase Inhibitor 100%
• Quantitative Structure-Activity Relationship 50%
• Applicability Domain 50%
• Thermolysin 50%

Chemistry

• mutagenic 33%