Musculoskeletal Tissue Engineering: Tendon, Ligament, and Skeletal Muscle Replacement and Repair

Jorge A. Uquillas, Settimio Pacelli, Shuichiro Kobayashi, Sebastián Uquillas

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva

2 Citas (Scopus)

Resumen

This chapter mainly focuses on the musculoskeletal muscle. It presents a brief explanation on the main techniques to engineer synthetic scaffolds with particular attention on their relevance in the field of tendon/ligament and skeletal muscle engineering. The strategy to repair tendon, ligaments, and skeletal muscles using synthetic materials are generally based on the fabrication of structures that mimic the native tissue organization and its functional properties. To achieve this goal, several methods have been proposed so far, including electrospinning, knitting or braiding, and micropatterning. Cell-based therapies with or without the presence of a scaffold represent an alternative strategy for tendon and ligament repair as well for skeletal muscle regeneration. Stem cells in tendon/ligament and skeletal muscle tissue engineering can be divided into three main classes: embryonic stem cells (ESCs), induced pluripotent stem cells (IPSs), and mesenchymal stem cells (MSCs).

Idioma originalInglés
Título de la publicación alojadaTissue Engineering for Artificial Organs
Subtítulo de la publicación alojadaRegenerative Medicine, Smart Diagnostics and Personalized Medicine
EditorialWiley-VCH Verlag
Páginas465-523
Número de páginas59
Volumen2-2
ISBN (versión digital)9783527689934
ISBN (versión impresa)9783527338634
DOI
EstadoPublicada - 1 ene. 2016
Publicado de forma externa

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