TY - JOUR
T1 - Omicron Sub-Lineages (BA.1.1.529 + BA.*) Current Status in Ecuador
AU - USFQ-COVID-19 Consortium
AU - CRN Influenza y OVR—INSPI
AU - Carrazco-Montalvo, Andrés
AU - Herrera-Yela, Andrés
AU - Alarcón-Vallejo, Damaris
AU - Gutiérrez-Pallo, Diana
AU - Armendáriz-Castillo, Isaac
AU - Andrade-Molina, Derly
AU - Muñoz-Mawyin, Karen
AU - Fernández-Cadena, Juan Carlos
AU - Morey-León, Gabriel
AU - Carvajal, Mateo
AU - Muñoz, Erika
AU - Guevara, Rommel
AU - Márquez, Sully
AU - Prado-Vivar, Belén
AU - Grunauer, Michelle
AU - Trueba, Gabriel
AU - Rojas-Silva, Patricio
AU - Barragan, Verónica
AU - Cárdenas, Paúl
AU - Bruno, Alfredo
AU - Garcés, Jimmy
AU - Olmedo, Maritza
AU - Páez, Michelle
AU - Armas-Gonzalez, Rubén
AU - Patiño, Leandro
N1 - Publisher Copyright:
© 2022 by the author. Licensee MDPI, Basel, Switzerland.
PY - 2022/6
Y1 - 2022/6
N2 - The Omicron variant of SARS-CoV-2 is the latest pandemic lineage causing COVID-19. Despite having a vaccination rate ≥ 85%, Ecuador recorded a high incidence of Omicron from De-cember 2021 to March 2022. Since Omicron emerged, it has evolved into multiple sub-lineages with distinct prevalence in different regions. In this work, we use all Omicron sequences from Ecuador available at GISAID until March 2022 and the software Nextclade and Pangolin to identify which lineages circulate in this country. We detected 12 different sub-lineages (BA.1, BA.1.1, BA.1.1.1, BA.1.1.14, BA.1.1.2, BA.1.14, BA.1.15, BA.1.16, BA.1.17, BA.1.6, BA.2, BA.2.3), which have been re-ported in Africa, America, Europe, and Asia, suggesting multiple introduction events. Sub-lineages BA.1 and BA.1.1 were the most prevalent. Genomic surveillance must continue to evaluate the dynamics of current sub-lineages, the early introduction of new ones and vaccine efficacy against evolving SARS-CoV-2.
AB - The Omicron variant of SARS-CoV-2 is the latest pandemic lineage causing COVID-19. Despite having a vaccination rate ≥ 85%, Ecuador recorded a high incidence of Omicron from De-cember 2021 to March 2022. Since Omicron emerged, it has evolved into multiple sub-lineages with distinct prevalence in different regions. In this work, we use all Omicron sequences from Ecuador available at GISAID until March 2022 and the software Nextclade and Pangolin to identify which lineages circulate in this country. We detected 12 different sub-lineages (BA.1, BA.1.1, BA.1.1.1, BA.1.1.14, BA.1.1.2, BA.1.14, BA.1.15, BA.1.16, BA.1.17, BA.1.6, BA.2, BA.2.3), which have been re-ported in Africa, America, Europe, and Asia, suggesting multiple introduction events. Sub-lineages BA.1 and BA.1.1 were the most prevalent. Genomic surveillance must continue to evaluate the dynamics of current sub-lineages, the early introduction of new ones and vaccine efficacy against evolving SARS-CoV-2.
KW - COVID-19
KW - Ecuador
KW - Omicron
KW - sub-lineages
UR - http://www.scopus.com/inward/record.url?scp=85132853923&partnerID=8YFLogxK
U2 - 10.3390/v14061177
DO - 10.3390/v14061177
M3 - Artículo
C2 - 35746651
AN - SCOPUS:85132853923
SN - 1999-4915
VL - 14
JO - Viruses
JF - Viruses
IS - 6
M1 - 1177
ER -
