Shear forces

Jose F. Alvarez-Barreto, Samuel B. Van Gordon, Brandon W. Engebretson, Vasillios I. Sikavitsas

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva


Modulation of cell function is a common, crucial aspect of tissue engineering approaches. It has been well understood from the very beginning that the success of tissue engineered constructs depends on the capacity of the cellular component to generate an extracellular matrix (ECM) that closely resembles the native one. is resemblance occurs at dierent levels; not only is it important to obtain an ECM with a molecular composition similar to that found in vivo, but it must also posses topographical and morphological assets that provide the cells an in vivo-like surface where they can properly function. Both aspects will in turn regulate cell function at the site of implantation and thereby aect tissue formation. It is therefore important to stimulate cells to generate an ECM with the aforementioned characteristics.

Idioma originalInglés
Título de la publicación alojadaTissue Engineering
Subtítulo de la publicación alojadaPrinciples and Practices
EditorialCRC Press
ISBN (versión digital)9781439874035
ISBN (versión impresa)9781439874004
EstadoPublicada - 1 ene. 2012
Publicado de forma externa


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