Symptomatic hemorrhage after alteplase therapy not due to silent ischemia

Michael D. Hill; Philip A. Barber; Andrew M. Demchuk; Robert J. Sevick; Richard Frayne; Alastair M. Buchan

doi:10.1186/1471-2377-1-1

Symptomatic hemorrhage after alteplase therapy not due to silent ischemia

Michael D. Hill^*
, Philip A. Barber
, Andrew M. Demchuk
, Robert J. Sevick
, Richard Frayne
, Alastair M. Buchan

^*Autor correspondiente de este trabajo

University of Calgary

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

8 Citas (Scopus)

Resumen

Background: Stroke thrombolysis-related intracerebral hemorrhage may occur remotely from the anatomical site of ischemia. One postulated mechanism for this is simultaneous multiple embolization with hemorrhage into a "silent" area of ischemia. Results: A patient suffered a disabling stroke affecting the right cerebral hemisphere. He was treated with intravenous alteplase and underwent extensive early imaging with multimodal MRI. Several hours after treatment he developed a brainstem hemorrhage despite having no evidence of ischemia on DWI MRI in the brainstem. Conclusion: Not all occurrences of remote ICH after stroke thrombolysis are secondary to multiple emboli with silent ischemia.

Idioma original	Inglés
Número de artículo	1
Publicación	BMC Neurology
Volumen	1
DOI	https://doi.org/10.1186/1471-2377-1-1
Estado	Publicada - 19 ene 2001
Publicado de forma externa	Sí

Acceder al documento

10.1186/1471-2377-1-1

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

@article{b429587f000748eea61db9e9f6b9f11c,

title = "Symptomatic hemorrhage after alteplase therapy not due to silent ischemia",

abstract = "Background: Stroke thrombolysis-related intracerebral hemorrhage may occur remotely from the anatomical site of ischemia. One postulated mechanism for this is simultaneous multiple embolization with hemorrhage into a {"}silent{"} area of ischemia. Results: A patient suffered a disabling stroke affecting the right cerebral hemisphere. He was treated with intravenous alteplase and underwent extensive early imaging with multimodal MRI. Several hours after treatment he developed a brainstem hemorrhage despite having no evidence of ischemia on DWI MRI in the brainstem. Conclusion: Not all occurrences of remote ICH after stroke thrombolysis are secondary to multiple emboli with silent ischemia.",

author = "Hill, \{Michael D.\} and Barber, \{Philip A.\} and Demchuk, \{Andrew M.\} and Sevick, \{Robert J.\} and Richard Frayne and Buchan, \{Alastair M.\}",

year = "2001",

month = jan,

day = "19",

doi = "10.1186/1471-2377-1-1",

language = "Ingl{\'e}s",

volume = "1",

journal = "BMC Neurology",

issn = "1471-2377",

publisher = "BioMed Central Ltd",

}

TY - JOUR

T1 - Symptomatic hemorrhage after alteplase therapy not due to silent ischemia

AU - Hill, Michael D.

AU - Barber, Philip A.

AU - Demchuk, Andrew M.

AU - Sevick, Robert J.

AU - Frayne, Richard

AU - Buchan, Alastair M.

PY - 2001/1/19

Y1 - 2001/1/19

N2 - Background: Stroke thrombolysis-related intracerebral hemorrhage may occur remotely from the anatomical site of ischemia. One postulated mechanism for this is simultaneous multiple embolization with hemorrhage into a "silent" area of ischemia. Results: A patient suffered a disabling stroke affecting the right cerebral hemisphere. He was treated with intravenous alteplase and underwent extensive early imaging with multimodal MRI. Several hours after treatment he developed a brainstem hemorrhage despite having no evidence of ischemia on DWI MRI in the brainstem. Conclusion: Not all occurrences of remote ICH after stroke thrombolysis are secondary to multiple emboli with silent ischemia.

AB - Background: Stroke thrombolysis-related intracerebral hemorrhage may occur remotely from the anatomical site of ischemia. One postulated mechanism for this is simultaneous multiple embolization with hemorrhage into a "silent" area of ischemia. Results: A patient suffered a disabling stroke affecting the right cerebral hemisphere. He was treated with intravenous alteplase and underwent extensive early imaging with multimodal MRI. Several hours after treatment he developed a brainstem hemorrhage despite having no evidence of ischemia on DWI MRI in the brainstem. Conclusion: Not all occurrences of remote ICH after stroke thrombolysis are secondary to multiple emboli with silent ischemia.

UR - https://www.scopus.com/pages/publications/2642532966

U2 - 10.1186/1471-2377-1-1

DO - 10.1186/1471-2377-1-1

M3 - Artículo

C2 - 11208259

AN - SCOPUS:2642532966

SN - 1471-2377

VL - 1

JO - BMC Neurology

JF - BMC Neurology

M1 - 1

ER -

Symptomatic hemorrhage after alteplase therapy not due to silent ischemia

Resumen

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto