TY - JOUR
T1 - The preventive and inhibitory effects of red raspberries on cancer
AU - Qi, Zexiu
AU - Yang, Bei
AU - Giampieri, Francesca
AU - Cianciosi, Danila
AU - Alvarez-Suarez, José Miguel
AU - Elexpuru-Zabaleta, Maria
AU - Quiles, Josè L.
AU - Forbes-Hernandez, Tamara Y.
AU - Zhang, Di
AU - Bai, Weibin
AU - Tian, Lingmin
AU - Mezzetti, Bruno
AU - Battino, Maurizio
AU - Armas Diaz, Yasmany
N1 - Publisher Copyright:
© 2024 - IOS Press. All rights reserved.
PY - 2024/3/19
Y1 - 2024/3/19
N2 - Red raspberries are gaining attention more and more for their nutritional and bioactive components, with potential health effects such as antitumor properties. This review aims to describe the antioxidant activities of red raspberries, emphasizing the role of anthocyanins and ellagitannins as primary contributors among red raspberry polyphenols; it also outlined the connection between red raspberries and their role in inhibiting cancer cell growth by regulating oxidative stress. Numerous studies suggest that red raspberries are able to block cancer cell progression by inhibiting proliferation, migration, and autophagy, as well as regulating the cell cycle, angiogenesis, and DNA damage repair. This review sheds light to the growing evidence supporting antioxidants as a crucial link between fruit consumption and cancer prevention.
AB - Red raspberries are gaining attention more and more for their nutritional and bioactive components, with potential health effects such as antitumor properties. This review aims to describe the antioxidant activities of red raspberries, emphasizing the role of anthocyanins and ellagitannins as primary contributors among red raspberry polyphenols; it also outlined the connection between red raspberries and their role in inhibiting cancer cell growth by regulating oxidative stress. Numerous studies suggest that red raspberries are able to block cancer cell progression by inhibiting proliferation, migration, and autophagy, as well as regulating the cell cycle, angiogenesis, and DNA damage repair. This review sheds light to the growing evidence supporting antioxidants as a crucial link between fruit consumption and cancer prevention.
KW - Red raspberry
KW - anthocyanins
KW - cancer
KW - ellagitannins
KW - oxidative stress
UR - http://www.scopus.com/inward/record.url?scp=85188778089&partnerID=8YFLogxK
U2 - 10.3233/JBR-240004
DO - 10.3233/JBR-240004
M3 - Artículo
AN - SCOPUS:85188778089
SN - 1878-5093
VL - 14
SP - 61
EP - 71
JO - Journal of Berry Research
JF - Journal of Berry Research
IS - 1
ER -